Directory » SUSAN BLOOMFIELD
KINESIOLOGY AND SPORT MANAGEMENT
SUSAN BLOOMFIELD (Emeritus)
Research Professor (Emeritus)
Adaptations of the Adult Skeleton to Exercise, Disuse, and Microgravity
Caloric Restriction Impact on Bone
Dr. Bloomfield gained her B.S. in Biology at Oberlin College (Ohio). After completing an M.A. in Physical Education at the University of Iowa and her Ph.D. in Exercise Physiology at The Ohio State University, Dr. Bloomfield joined the faculty in Health & Kinesiology at Texas A&M in 1993. Her research interests focus on the integrative physiology of bone, with specific reference to skeletal adaptations to disuse, microgravity, caloric deficiency, and inflammation. Dr. Bloomfield is a Fellow in the American College of Sports Medicine and in the National Academy of Kinesiology. Her research was funded for 20+ years by the National Space Biomedical Research Institute, NASA, and Department of Defense. A frequent member of NASA advisory panels, Dr. Bloomfield also served on two National Academy committees advisory to NASA for 5 years. Dr. Bloomfield served as Asst. Provost in the Office of Graduate and Professional Studies from 2012-2016 and, from 2016-2020, as Associate Dean for Research in the College of Education & Human Development, overseeing CEHD Research & Development Office staff and functions.
Ph.D., Exercise Physiology, Ohio State University (1992)
M.A., Exercise Physiology, University of Iowa (1978)
B.A., Biology, Oberlin College, Ohio (1974)
KINE433. PHYSIOLOGY OF EXERCISE
KINE439. Exercise Eval And Prescp
KINE485. Directed Studies
KINE485. DIRECTED STUDIES
KINE485. Directed Studies-honors
KINE489. Special Topics In Cntrvrs In Ex Scien
KINE489. Special Topics In Cntrvrs In Education Sci
KINE491. Research: Honors
KINE626. Exercise Clin Population
KINE682. SEMINAR IN
KINE682. Seminar In
KINE684. PROF INTERNSHIP
KINE685. DIRECTED STUDIES
KINE685. Directed Studies
FORMER DOCTORAL STUDENTS
Sarah Little, Ph.D. (Spring 2020)
Rihana Bokhari (Summer 2018)
Corinne Elizabeth Metzger (Spring 2018)
Ramon Boudreaux (Spring 2014)
Yasaman Shirazi-Fard (in Biomedical Engineering), Ph.D. (Spring 2013)
Brandon Macias (Fall 2012)
Sibyl Swift (in Nutrition), Ph.D. (Summer 2010)
Joshua Swift, Ph.D. (Spring 2010)
Kyunghwa Baek (in Nutrition) (Fall 2007)
Matthew Allen (Summer 2003)
Metzger CE, Narayanan A, Zawieja DC, Bloomfield SA. Inflammatory bowel disease in a rodent model alters osteocyte protein levels controlling bone turnover. J Bone Miner Res (in press) DOI: 10.1002/jbmr.3027
Narayanan A*, Metzger CE*, Bloomfield SA, Zawieja DC. Inflammation-induced lymphatic architecture and bone turnover changes are ameliorated by irisin treatment in chronic inflammatory bowel disease. FASEB J (in press)
Lang T, Van Loon JWA, Bloomfield S, Vico L, Chopard A, RittwegerJ, Kyparos A, Blottner D, Vuori I, Gerzer R, Cavanagh PR. Towards human exploration of space: the THESEUS review series on muscle and bone research priorities. npj Microgravity 3: Article 8. 2017. DOI: 10.1038/s41526-017-0013-0.
Metzger CE, Brezicha JE, Elizondo JP, Narayanan A, Hogan HA, Bloomfield SA. Differential responses of mechano-sensitive osteocyte proteins in forelimbs and hindlimbs in hindlimb unloaded rats. Bone 105: 26-34, 2017.
Metzger CE*, Narayanan A*, Zawieja DC, Bloomfield SA. Inflammatory bowel disease in a rodent model alters osteocyte protein levels controlling bone turnover. J Bone Miner Res 32: 802-813, 2017. DOI: 10.1002/jbmr.3027
Bloomfield SA, Martinez DA, Boudreaux RD, Mantri AV. Microgravity stress: Bone and connective tissue. Comp Physiol 6: 645-686, 2016.
Macias BR, Lima F, Swift JM, Shirazi-Fard Y, Greene ES, Allen MR, Fluckey J, Hogan HA, Braby L, Wang S, Bloomfield SA. Simulating the Lunar environment: Partial weightbearing and high-LET radiation induce bone loss and increase sclerostin-positive osteocytes. Radiat Res 186: 254-263, 2016
Metzger CE, Baek K, Swift SN, De Souza MJ, Bloomfield SA. Exercise during energy restriction mitigates bone loss but not alterations in estrogen status or metabolic hormones. Osteoporosis Int 27(9): 2755-2764, 2016.
Ritchie LE, Taddeo SS, Weeks BR, Lima F, Bloomfield SA, Azcarate-Peril M, Zwart SR, Smith SM, Turner ND. Space environmental factor impacts upon murine colonic microbiota and mucosal homeostasis. PLoS One 10 (6): e0125792, 2015
Boudreaux RD, Metzger CE, Macias BR, Shirazi-Fard Y, Hogan HA, Bloomfield SA. Bone loss during partial weightbearing (1/6th gravity) is mitigated by resistance and aerobic exercise in mice. Acta Astronautica 99: 71-77, 2014
Boudreaux RD, Swift JM, Gasier HG, Wiggs MP, Hogan HA, Fluckey JA, Bloomfield SA. Increased resistance during jump exercise does not enhance cortical bone formation. Med Sci Sports Exerc 46(5): 982-989, 2014
Ploutz-Snyder L, Bloomfield S, Smith SM, Hunter SK, Templeton K, Bemben D. Effects of sex and gender on adaptation to space: musculoskeletal health. J Women19s Health 23: 963-966, 2014.
Shirazi-Fard Y, Metzger CE, Kwaczala AT, Judex S, Bloomfield SA, Hogan HA. Moderate intensity resistive exercise improves metaphyseal cancellous bone recovery following an initial disuse period, but does not mitigate decrements during a subsequent disuse period in adult rats. Bone 66: 296-305, 2014.
Swift JM, Swift SN, Allen MR, Bloomfield SA. Beta-1 adrenergic agonist treatment mitigates negative changes in cancellous bone microarchitecture and inhibits osteocyte apoptosis during disuse. PLoS One 9: e106904, 2014.
Swift SN, Swift JM, Bloomfield SA. Mechanical loading increases detection of estrogen-alpha receptors in osteocytes and osteoblasts despite chronic energy restriction. J Appl Physiol 117: 1349-1355, 2014
Shirazi-Fard Y, Anthony RA, Kwaczala AT, Judex S, Bloomfield SA, Hogan HA. Previous exposure to simulated microgravity does not exacerbate bone loss during subsequent exposure in the proximal tibia of adult rats. Bone 56(2): 433-43, 2013
Shirazi-Fard Y, Kupke JS, Bloomfield SA, Hogan HA. Discordant recovery of bone mass and mechanical properties during prolonged recovery from disuse. Bone 52(1): 433-43, 2013
Swift JM, Hogan HA, Bloomfield SA. Beta-1 adrenergic agonist mitigates unloading-induced bone loss by maintaining formation. Med Sci Sports Exerc 45(9): 1665-1673, 2013
Swift JM, Lima F, Macias BR, Allen MR, Greene ES, Shirazi-Fard Y, Kupke JS, Hogan HA, Bloomfield SA. Partial weightbearing does not prevent musculoskeletal losses associated with disuse. Med Sci Sports Exerc 45(11): 2052-2060, 2013
Baek K, Bloomfield SA. Blocking 3B2-adrenergic signaling attenuates reductions in circulating leptin, cancellous bone mass , and marrow adiposity seen with dietary energy restriction. J Appl Physiol 113: 1792-1801, 2012
Macias BR, Swift JM, Nilsson MI, Hogan HA, Bouse SD, Bloomfield SA. Simulated resistance training, but not alendronate, increases cortical bone formation and suppresses sclerostin during disuse. J Appl Physiol 112: 918-925, 2012
Swift SN, Baek K, Swift JM, Bloomfield SA. Restriction of dietary energy intake has a greater impact on bone integrity than does restriction of calcium in exercising female rats. J Nutr. 142: 1038-1045, 2012
Kim W-K, Bloomfield SA, Ricke SC. Effects of age, vitamin D3, and fructooligosaccharides on bone growth and skeletal integrity of broiler chicks. Poultry Sci 90: 2425-2432, 2011
Swift J.M., S.N Swift., M.I. Nilsson, H.A. Hogan, S.D. Bouse, and S.A. Bloomfield. Cancellous bone formation response to simulated resistance training during disuse is blunted by concurrent alendronate treatment. J Bone Miner Res 26: 2140-2150, 2011
Carpenter, R.D., T.F. Lang, S.A. Bloomfield, J.J. Bloomberg, S. Judex, J.H. Keyak, R.J. Midura, P.D.Pajevic, J.M. Spatz. (2010) Effects of long-duration spaceflight, microgravity, and radiation on the neuromuscular, sensorimotor, and skeletal systems. J. Cosmology 12: 3778-3780.
Swift JM, Gasier HG, Swift SN, Wiggs, MP, Hogan HA, Fluckey JD and Bloomfield SA. Increased training loads do not magnify cancellous bone gains with rodent jump resistance exercise. J Appl Physiol, 109: 1600-7, 2010
Swift, J.M., H.A. Hogan, M.I. Nilsson, L.R. Sumner, and S.A. Bloomfield. (2010). Simulated resistance training during hindlimb unloading abolishes disuse bone loss and maintains muscle strength. J. Bone Miner. Res. 25: 564-574.
Baek, K. and S. Bloomfield. (2009). Beta-adrenergic blockade and leptin replacement effectively mitigate disuse bone loss. J of Bone and Mineral Research.
Baek, K., A.A. Barlow, M.R. Allen, and S.A. Bloomfield Food restriction andsimulated microgravity: effects on bone and serum leptin. J. Appl. Physiol. 104: 1086-1093, 2008
Prisby, R.D., J.M. Swift, S.A. Bloomfield, H.A. Hogan, and M.D. Delp (2008) Alterations in bone mass, geometry and mechanical properties in the fatty Zucker rat model for Type II diabetes. J. Endocrinology Published online 28 Aug 2008, DOI: 10.1677/JOE-08-0046
Kim, W-.K., L.M. Donalson, S.A. Bloomfield, H.A. Hogan, L.F. Kubena, D.J. Nisbet, and S.C. Ricke.,(2007). Molt performance and bone density of cortical, medullary, and cancellous bone is laying hens during feed restriction or alfalfa-based feed molt. Poultry Sci. 86:1821-1830.
Wallace, J.M., R.M. Rajachar, M.R. Allen, S.A. Bloomfield, P.G. Robey, M.F. Young, and D.H. Kohn. (2007). Exercise-induced changes in the cortical bone of growing mice are bone- and gender-specific. Bone. 40: 1120-1127.
Allen MR, Hogan HA and Bloomfield SA. Differential bone and muscle recovery following hindlimb unloading in skeletally mature male rats. J Musculoskeletal Neuronal Interact 6: 217-225, 2006.
Wallace, J.M., R.M. Rajachar, X.-D. Chen, S. Shi, M.R. Allen, S.A. Bloomfield, C.M. Les, P.G. Robey, M.F. Young, and D.H. Kohn. (2006). The phenotype of biglycan-deficient mice is bone- and gender-specific. Bone 39: 106-116.
Bloomfield, S.A. (2005). Contributions of physical activity to bone health over the lifespan. Topics in Geriatric Rehab. 21: 68-76.
Hubal, M.J., Ingalls, C.P., Allen, M.R., Wenke, J.C., Hogan, H.A., Bloomfield, S.A. (2005). Effects of eccentric exercise training on cortical bone and muscle strength in the estrogen deficient mouse. Journal of Applied Physiology 98: 1674-1681.
Kohrt, W.M., Bloomfield, S.A., Little, K.D., Nelson, M.E. & Yingling, V.R. (2004). ACSM position stand: Physical activity and bone health. Medicine and Science in Sports and Exercise 36: 1985-1996.
Narayanan, R., Allen, M.R., Gaddy, D., Bloomfield, S.A., Smith, C.L., & Weigel, N.L. (2004). Differential skeletal responses of hindlimb unloaded rats on a Vitamin D deficient diet to 1,25 dihydroxyvitamin D and its analog, Seocalcitol (EB1098). Bone, 35, 134-143.
Warren, G.L., Stallone, J.L., Allen, M.R., & Bloomfield, S.A. (2004). Functional recovery of the plantarflexor muscle group after hindlimb unloading in the rat. European Journal of Applied Physiology 93: 130-138.
Yao, Z., Lafage-Proust, M-H., Plouet, J., Bloomfield, S., Alexandre, C., & Vico, L. (2004). Increase of both angiogenisis and bone mass in response to exercise depends on VEGF. Journal of Bone and Mineral Research 19: 1471-1480.
Allen, M.R. and S.A. Bloomfield. (2003). Hindlimb unloading has a greater effect on cortical compared to cancellous bone in mature female rats. Journal of Applied Physiology, 94, 642-650.
Chen, X.-D., M.R. Allen, S. Bloomfield, T. Xu and M. Young. (2003). Biglycan deficient mice have delayed osteogenesis after marrow ablation. Calcif. Tiss. Int. 72: 577-582.
Mekraldi, S., M.-H. Lafage-Proust, S. Bloomfield, C. Alexandre and L. Vico. (2003). Changes in vasoactive factors associated with altered vessel morphology in the tibial metaphysis during ovariectomy-induced bone loss in rats. Bone 32: 630-641.
Nielsen, K.L., Allen, M.R., Bloomfield, S.A., Andersen, T.L., Chen, X.D., Xu, T., Poulsen, H.S., Young, M.F., & Heegaard, A.M. (2003). Biglycan deficiency interferes with ovariectomy-induced bone loss. Journal of Bone and Mineral Research, 18, 2152-2158.
Bloomfield, S.A., Allen, M.R., Hogan, H.A., & Delp, M.D. (2002). Site-and compartment-specific changes in bone with hindlimb unloading in mature adult rats. Bone 31(1), 149-157.
Bloomfield, S.A., Hogan, H.A., & Delp, M.D. (2002). Decreases in bone blood flow and bone material properties in aging. Fischer-344 rats. Clin. Orthop. Rel. Rse, 396:248-257.
Colleran, P.N., Wilkerson, M.K., Bloomfield, S.A., Suva, L.J., Turner, R.T. and Delp, M.D. (2000). Alterations in skeletal perfusion with simulated microgravity: A possible mechanism for bone remodeling. J. Appl. Physiol. 89, 1046-1054 .
Hubal, M.J., C.P. Ingalls, M. Allen, J.C. Wenke, and S.A. Bloomfield. (2000). Effects of eccentric exercise training on mouse skeletal muscle and bone. Med. Sci. Sport Exerc. 32(5, Suppl.): S270.
Allen, M.R., C.P. Ingalls, G.L. Warren, and S.A. Bloomfield. (1999). Time course of bone and muscle alterations after hindlimb suspension and 24-hour reambulation in mice. J. Bone Miner. Res. 14 (Suppl. 1): S217.
Inman, C. L., G.L. Warren, H.A. Hogan, and S.A. Bloomfield. (1999). Mechanical loading attenuates bone loss due to immobilization and calcium deficiency. J. Appl. Physiol. 87(1): 189-195.
Turner, R.T., T.J. Wronski, M. Zhang, L.S. Kidder, S.A. Bloomfield, and J.D. Sibonga. (1998). Effects of ethanol on gene expression in rat bone: transient dose-dependent changes in mRNA levels for matrix proteins, skeletal growth factors, and cytokines are followed by reductions in bone formation, Alcohol Clin. Experimental Research, 22(7), 1591-1599.
Bloomfield SA and Metzger CE. Novel findings in bone biology: impact on bone health for women. In: Spangenburg, E (ed). Integrative Biology of Women19s Health. (New York, NY: Springer), 2013; pp. 17-33
Carpenter, R.D., T.F. Lang, S.A. Bloomfield, J.J. Bloomberg, S. Judex, J.H. Keyak, R.J. Midura, P.D.Pajevic, J.M. Spatz. (2010) in: The Human Mission to Mars: Colonizing the Red Planet, pg 245-267. (City): Cosmology Science Publishers.
Bloomfield, S.A. and S.S. Smith. (2003). Osteoporosis. In: J.L. Durstine and G.E. Moore (Eds.). American College of Sport Medicine's Exercise Management for Persons with Chronic Diseases and Disabilities, 2nd edition. Pp.222-229. Champaign, IL: Human Kinetics.
Warner, S.A. & Bloomfield, S.A. (2001). Deconditioning and Best Rest: Induced Effects on Bone Health. In: J.L. Roitman (Ed.). American College of Sports Medicine Resource Manual for Guidelines for Exercise Testing and Prescription, 4th edition. Baltimore: Williams and Wilkins, pp. 195-199.
Other Publications and Presentations
Avin KG, Bloomfield SA, Gross TS, Warden SJ. Biomechanical aspects of the muscle-bone interaction. Curr Osteoporos Rep. 13(1): 1-8, 2015.
Bloomfield, S.A. (2010) Disuse osteopenia. Curr. Osteoporosis Rep. 8:91-97. [no IF listed; request 30 credits]
Bloomfield, S.A. (2001). Optimizing bone health: Impact of nutrition, exercise, and hormones. Gatorade Sports Science Institute Sports Science Exchange. 14(3), 1-4.
Will use of long-acting, reversible contraceptives impact musculoskeletal health of female rats in a simulated exploration class mission duration?
Inflamm-aging and bone loss in a rodent model of spinal cord injury
Inflamm-Aging and Bone Loss in a Rodent Model of Spinal Cord Injury
Retired Astronaut Medical Data Repository: a Feasibility Project
Maternal and Fetal Skeletal Impacts of Continuous, Low Dose-rate Neutron Radiation Exposure
Peripheral-nerve Electrical Stimulation to Prevent Bone Mineral Density Loss in the Lower Extremity after Spinal Cord Injury
T3 - Long-Term Health Impact of the Space Environment: Retired Astronaut Biomedical Data Repository
Fellowship Award - Heather Allaway - Will Use of Long-Acting, Reversible Contraceptives Mitigate Bone Loss in Female Rats During Simulated Exploration Class Missions?
The Benefits of Exercise During Disuse Extend Beyond Weight-bearing Alone
Mitigating Radiation-induced Bone Loss via Dietary Modulation of Enflammatory Cytokines
Long-term Impact of Continuous Radiation Exposure on Bone Cell Activity: Role of Exercise during Exposure
To Determine the Impact of Continuous Radiation Exposure on Measures of Bone Structural Integrity and Cell Activity in Exercising and Sedentary Animals
Modulation of Bone Response to Exercise and Disuse by Oral Contraceptive Use
(STUDENT: ANITA MANTRI) Modulation of Bone Response to Exercise and Disuse by Oral Contraceptive Use
(STUDENT: CORRINE METZGER) Bone response to chronic inflammation  response of osteocyte proteins
Sclerostin's Role in Regulating Bone Formation during Long-term Simulated Microgravity and Subsequent Recovery
Pre-Treatment Approaches for Improving the Response of Bone to Disuse and Recovery
Iron Overload and Oxidative Damage: Regulators of Bone Homeostasis in the Space Environment
Resistance Exercise and Bisphosphonate Therapy as a Novel Pre-Treatment to Prevent Bone Loss
Iron Overload, Radiation Exposure and Unloading: Interactive Impact on Bone
Sex Hormone Effects on the Recovery of Bone and Muscle Following Long-Term Simulated Weightlessness
Wnt Signaling in Bone During Reduced Gravity and in Response to Mechanical Loading
Wnt Signaling in Bone during Reduced Gravity and in Response to Mechanical Loading
The Effects of X-ray Low Dose Radiation on the Growth and Differentiation of Bone Marrow Stromal Cells in Rats
Is Estrogen Signaling Down-regulated with Chronic Dietary Energy Restriction in Exercising Females
Nutritional Amelioration of Radiation Damage and Muscle Loss Due to Inactivity
Contributors to Long-Term Recovery of Bone Strength following Exposure to Microgravity - NRA/Research and Technology Development to Support Crew Health and Performance in Space Exploration Missions
Maintaining Musculoskeletal Health in the Lunar Environment
Team Leader - Musculoskeletal Alterations Team
Statins, Cholesterol, and Exercise: Skeletal Muscle Hypertrophy versus Myopathy
Effects of Dietary Protein and Cholesterol and Flywheel Training on Muscle Strength, Neural Activation, Mass and Anabolic Poetential during Simulated Microgravity
Resistance Exercise and Cross-linking in Diabetic Bone
Assessing the Ability of a Non-specific Beta-adrenergic Receptor
Current Controversies in Exercise Science
Effects of Dietary Protein Timing and Dietary Cholesterol on Muscle Protein Synthesis, Hypertrophy and Function following Standard or Portable Flywheel Training
A B-Agonist Countermeasure for Bone/Muscle Loss with Unloading
Impact of Graded Energy Restriction on Bone Health in Exercising Female Rats
Optimizing bone development and skeletal reserves for egg production before sexual maturity to improve skeletal integrity, egg production, and eggshell quality in laying hens
Dobutamine as a Countermeasure for Bone and Muscle Loss with Immobilization
Psychological Effects of Short-Term Weight Loss and Weight Cycling on Bone Health and Menstrual Cyclicity in Premenopausal Women
Nutrient Restriction Effects on Bone in Exercising Females
An Autonomous Device for Patient Monitoring and Diagnosis
Food Restriction and Bone Health in Active Females
A Graduate Education Program Focusing on Space Life Sciences
Impact of Food Restriction on Bone Health in Active Females: Endocrine Mechanisms and Role of Dietary Calcium
NSBRI - Associate Team Leader - Bone Loss Team
Increasing the Efficiency of Exercise Countermeasures for Bone Loss
Bone and Muscle Recovery from Simulated Microgravity
NSBRI-Receptor Countermeasures to Bone Loss in Microgravity
NSBRI Associate Team Leader Funding - Bone Loss Team
NSBRI-Bone and Muscle Recovery from Simulated Microgravity
Bone Mineral Density, Geometry, and Mechanical Properties in Rate Bone
Novel Receptor-Based Countermeasures to Microgravity - Induced Bone Loss
NSBRI-Bone Demineralization/Calcium Metabolism
NSBRI-Bone Blood Flow and Microgravity
NSBRI-Bone Blood Flow and Microgravity
NSBRI-Bone Demineralization/Calcium Metabolism
Bone Blood Flow During Simulated Microgravity: Physiological and Molecular Mechanisms
Effects of Aging on Bone Geometric Properties.
The Effects of Partial Mechanical Loading and Ibandronate on Skeletal Tissues in the Adult Rat Hindquarter Suspension Model of Microgravity
American College of Sports Medicine Citation Award (2nd Highest Award given nationally) (2016)
Fellow, American College of Sports Management. (1997)
Orthopaedic Research Society Musculoskeletal Biology Workshop RIB (Research-in-Bone) Award (2021)
Outstanding New Faculty. TAMU. (1994)
Texas A&M Dept. of Health & Kinesiology R.B. Armstrong Research Scholar Award. (2011)
Texas Regional Chapter ACSM Service Award (2021)
Visiting Scholar Award. American College of Sports Medicine. (1993)
Associate Editor. Clinical Exercise Physiology (1998 - 2002)
Editorial Board Member. Medicine and Science in Sports and Exercise (2005 - 2012)
Associate Lead, Bone/Musculoskeletal Alterations Team, National Space Biomedical Research Institute. (2000-2012)
Board of Trustees-3 yr. Term. American College of Sports Medicine. (2000)
Councilor, Environment & Exercise Physiology Section, American Physiological Society. (2009)
Faculty Mentor. NSBRI Space Life Science Fellow program. (2011)
Fellow, National Academy of Kinesiology (2017)
President, Texas Regional Chapter of the American College of Sports Medicine (2000)