Directory » J TIMOTHY LIGHTFOOT
tlightfoot@tamu.edu
121 PDC-WC
979-845-8744
Department
HEALTH & KINESIOLOGY
Kinesiology

J TIMOTHY LIGHTFOOT
Professor & Director| Huffines Institute
HEALTH & KINESIOLOGY
Curriculum Vitae
BIOGRAPHY
Dr. J. Timothy Lightfoot is currently the Debbie and Mike Hilliard Endowed Professor of Kinesiology and the Director of the Sydney and JL Huffines Institute for Sports Medicine and Human Performance at Texas A&M University. Dr. Lightfoot received his Bachelors and Masters degrees from University of Louisiana Monroe and his doctorate from the University of Tennessee. He completed a research consultantship with the United States National Aeronautics and Space Administration (NASA) at Kennedy Space Center in the Biomedical Laboratory and then a three-year National Institute of Health postdoctoral research fellowship in the Division of Physiology at Johns Hopkins University. He was an Assistant and Associate Professor at Florida Atlantic University for 6 years (two years as Department Chair), and a Professor at the University of North Carolina Charlotte for 14 years, 9 years of which he was Chair of the department. Dr. Lightfoot has published over 85 scientific, peer-reviewed articles on the genetics of daily physical activity and exercise endurance, as well as the physiological response to high-G exposure and hemorrhage and thus far has had ≈ $3 million in external funding from the National Institutes of Health and Department of Defense to conduct research on the genetics of physical activity. His lab also has a unique interest in the physiological responses of athletes in a variety of non-traditional venues such as auto racing and in musicians. His research has been featured in numerous general media outlets including the Los Angeles Times, the New York Times, Time.com, National Public Radio, the Rush Limbaugh show, CNN, the NBC Today Show, MSNBC, Revista Epoca (a Brazilian weekly magazine), and on Australian National Radio.

Dr. Lightfoot is a Fellow of the American College of Sports Medicine, an ACSM Certified Exercise Physiologist, an ACSM Registered Clinical Exercise Physiologist, a Past-President of the Southeast Regional Chapter of the American College of Sports Medicine, and a past member of the Board of Trustees for the American College of Sports Medicine. He was awarded the national ACSM Citation Award in May 2018 and was named University Graduate Student Mentor of the Year at Texas A&M in 2018. He has been named Teacher of the Year in his College at three different Universities (Florida Atlantic University, University of North Carolina Charlotte, and at Texas A&M University) and was awarded the Henry Montoye Research Scholar Award by the Southeast American College of Sports Medicine in 2010. He was named Alumnus of the Year of the University of Louisiana Monroe in Kinesiology in 2010 and at the University of Tennessee in 2016, gave the keynote lecture at the 2013 Performing Arts Medical Association meeting, the President’s Keynote Lecture at the 2014 national American College of Sports Medicine meeting, the Keynote Speaker at the 2018 Southeast American College of Sports Medicine meeting, and was recently named the Pease Family Scholar Speaker at Iowa State University. He is a native Texan, married to a brilliant and beautiful woman (Faith), is the co-founder of the company Academic Career Development Services, used to race automobiles for fun, and has a passion for playing the bass guitar, which he does in live settings with a variety of bands.
NATIONAL PROFESSIONAL SERVICE
Chair, American College of Sports Medicine Science Integration & Leadership Committee (2016-2019) Member, American College of Sports Medicine Publications Committee (2016-2019) Member and Former Chair, American College of Sports Medicine Task Force on Motorsports Safety (2001-current) Associate Editor, Medicine and Science in Sports and Exercise (2015-2018) Member and Founding Member of National Exercise Clinical Trials Network (NExTNet), (2013-current)
COURSES TAUGHT
KINE433. PHYSIOLOGY OF EXERCISE
2014C
KINE491. RESEARCH
2018C,2018A,2017A,2016C,2015C
KINE609. PRO CAREER DEV HLTH KINE
2019A,2017A
KINE614. EXTERNAL RESEARCH FUND DEVELOP
2020A,2018A
KINE629. PHYSIOLOGY STRENGTH COND
2020A
KINE630. PERIODIZED MODELS
2020A
KINE681. SEMINAR
2019C
KINE682. SEMINAR IN
2013C
KINE683. PRACTICUM IN KINESIOLOGY
2020B
KINE684. PROF INTERNSHIP
2020C
KINE685. DIRECTED STUDIES
2020C,2020B,2020A,2019C,2019B
KINE689. SPECIAL TOPICS IN
2016A,2015A,2013A,2012A
FORMER DOCTORAL STUDENTS
Jorge Granados (Fall 2019)
Ayland Cash Letsinger (Summer 2019)
Heather Leigh Vellers (Summer 2016)
Emily Schmitt (Spring 2015)
David Fertuson (Summer 2013)
TEACHING AND STUDENT MENTORSHIP AWARDS
2018 - Distinguished University Graduate Mentoring Award - Texas A&M Association of Former Students 2017 - Fishcamp Namesake, Texas A&M University 2017 - Distinguished College Level Teaching Award - Texas A&M Association of Former Students 2001 - Graduate Teacher of the Year, College of Nursing and Health Professions, University North Carolina Charlotte / 1995 - Teacher of the Year, College of Education, Florida Atlantic University
SELECTED PUBLICATIONS
Books and Monographs
Lightfoot, JT, AC Letsinger*, JZ Granados*. The Evolution of Genetic Mechanisms Controlling Physical Activity. (Chapter 7), pp. 80-93. In: The Routledge Handbook of Sport and Exercise Systems Genetics. Lightfoot, Hubal, Roth (eds), Routledge Publishing, Cambridge, UK, 2019.
Bray, M.S., J.E. Fulton, N.S. Kalupahana, J.T. Lightfoot. (2011) Genetic Epidemiology, Physical Activity, and Inactivity. In, C. Bouchard and E.P. Hoffman (Eds.), Genetic and Molecular Aspects of Sport Performance: Volume XVIII of the Encyclopaedia of Sports Medicine, An IOC Medical Commission publication. Oxford, UK. Wiley-Blackwell
Kalupahana, N.S., N. Moustaid-Moussa, J.H. Kim, B.H. Voy, D. Bassett, M.S. Bray, J.T.Lightfoot. (2011) The regulation of physical activity by genetic mechanisms: Is there a drive to be active? In, C. Bouchard and E.P. Hoffman (Eds.), Genetic and Molecular Aspects of Sport Performance: Volume XVIII of the Encyclopaedia of Sports Medicine, An IOC Medical Commission publication. Oxford, UK. Wiley-Blackwell
Lightfoot, J.T. (2011) Can you be born a couch potato? The genomic regulation of physical activity. In, L.S. Pescatello and S.M. Roth (Eds.), Exercise Genomics. New York, NY: Humana Press
*Moore-Harrison, T, Lightfoot, JT "Driven to be Inactive?: The Genetics of Physical Activity" in Genetics of Adipose Tissue and Obesity (part of the series: Progress in Molecular Biology and Translational Science, formerly Progress in Nucleic Acid Research and Molecular Biology) Dr. C. Bouchard ed. Academic Press (division of Elsevier)
Bray, M.S., Fulton, JE, *Kalupahana, NS, Lightfoot, JT. [8220]Genetic Epidemiology, Physical Activity and Inactivity[8221] Genetic and Molecular Aspects of Sport Performance, in (one volume of the Encyclopaedia of Sports Medicine sponsored by the International Olympic Committee). Drs. E. Hoffman and C. Bouchard eds. Wiley- Blackwell
*Kalupahana, NS, Moustaid-Moussa, N, Kim, JH, Voy, BH, Bassett, D, Lightfoot, JT "The Regulation of Activity By Genetic Mechanisms: Is There a Drive to Be Active?" in Genetic and Molecular Aspects of Sport Performance, (one volume of the Encyclopaedia of Sports Medicine sponsored by the International Olympic Committee). Drs. E. Hoffman and C. Bouchard eds. Wiley-Blackwell
Journal Articles
Letsinger, A.C., J. Z. Granados, S. E. Little, J. Timothy Lightfoot. Alleles associated with physical activity levels are estimated to be older than anatomically modern humans. PLoS One. 14(4): e0216155. 2019. https://doi.org/10.1371/journal.pone.0216155,
Reid, M. B., JT Lightfoot. The Physiology of Auto Racing: A Brief Review. Medicine and Science in Sports and Exercise. 51(12): 2548-2562. 2019
Lightfoot, JT, EJC De Geus, FW Booth, MS Bray, M den Hoed, J Kaprio, SA Kelly, D Pomp, MC Saul, MA Thomis, T Garland Jr, C Bouchard. Biological / Genetic Regulation of Physical Activity Level: Consensus from GenBioPAC. Medicine and Science in Sports and Exercise. 50(4), 863-873. 2018. doi:10.1249/MSS.0000000000001499
Lightfoot, JT, MM Bamman, FW Booth. Translation Goes Both Ways: The Power of Reverse Translation from Human Trials into Animal Models. Translational Journal of the American College of Sports Medicine. 2(5): 29-31, 2017.
Vellers, HL*, AC Letsinger*, NR Walker*, JZ Granados*, JT Lightfoot. High Fat High Sugar Diet Reduces Voluntary Wheel Running in Mice Independent of Sex Hormone Involvement. Frontiers in Physiology -Exercise Physiology. 8: article 628 (doi: 10.3389/fphys.2017.00628), 2017.
Lightfoot, JT. The McArdle[8217]s Mouse Model: Providing Important Insight into Skeletal Muscle Regulation. Med. Sci. Sports Exerc. (Commentary) Med. Sci. Sports Exerc. 48(8): 1447, 2016
Schmitt EE*, HL Vellers*, WW Porter, JT Lightfoot. Environmental endocrine disruptor inhibits voluntary physical activity in mice. Med. Sci. Sports Exerc. 48 (7), 1251-1258, 2016
Dawes, M*, KJ Kochan, PK Riggs, JT Lightfoot. Differential miRNA expression in inherently high- and low-active inbred mice. Physiol. Reports 3:7 e12469-82, 2015.
Ferguson, DP*, A David, JT Lightfoot. Optimizing the physical conditioning of the NASCAR Sprint Cup pit crew athlete. J. Strength and Conditioning Research. 29(3): 567-577, 2015
Ferguson, DP*, LJ Dangott, HL Vellers*, EE Schmitt*, JT Lightfoot. Differential protein expression in the nucleus accumbens of high and low active mice. Behavioural Brain Research. 291: 283-288, 2015.
Oliver, J*, K Abbas, JT Lightfoot, K Baskin*, B Collins*, D Wier, JP Bramhall, J Huang, JB Puschett. Comparison of neurocognitive testing and the measurement of marinobufagenin in mild traumatic brain injury: a preliminary report. J. Exp. Neuroscience. 9: 67-72, 2015
Vellers, HL*, C Irwin*, JT Lightfoot. Heart rate response of professional musicians when playing music. Medical Problems of Performing Artists. 30: 100-105, 2015.
Dawes, M*, T Moore-Harrison*, AT Hamilton, T Ceaser*, KJ Kochan, PK Riggs, JT Lightfoot. Differential gene expression in high and low active inbred mice. BioMedical Research International. Vol. 2014, Article ID 361048, 9 pages, 2014. doi:10.1155/2014/361048. PMID: 24551844, PMCID: 3914289
deGeus, EJC, M Bartels, J Kaprio, JT Lightfoot, M Thomis. (2014) Genetics of regular exercise and sedentary behaviors. Twin Research and Human Genetics 17(4): 262-271
Ferguson, DP*, LJ Dangott, EE Schmitt*, HL Vellers*, JT Lightfoot. (2014) Differential skeletal muscle proteome of high- and low-active mice. Journal of Applied Physiology 116: 1057-1067
Ferguson, DP*, LJ Dangott, JT Lightfoot. (2014) Lessons learned from vivo-morpholinos: How to avoid vivo-morpholino toxicity. BioTechniques.56(5): 251-256
Lightfoot, JT, J Morton. (2014) The physiology of dancing and singing at the same time. Voice and Speech Review. 8(3):280-287
Bamman, MM, DM Cooper, FW Booth, ER Chin, PD Neufer, S Trappe, JT Lightfoot, WE Kraus, MJ Joyner. (2013) Exercise Biology and Medicine: Innovative Research to Improve Global Health. Mayo Clinic Proc. (In Press)
Ferguson, DP*, EE Schmitt*, JT Lightfoot. (2013) Vivo-morpholinos induced transient knockdown of physical activity related proteins. PLoS ONE. 8(4): e61472
Lightfoot, JT. (2013) [48]1CWhy Control Activity? Evolutionary selection pressures affecting the develop-ment of physical activity genetic and biologic regulation. Biomed Research International
Bowen, R.S., Knab, A.M, Hamilton, A.T., McCall, J.R., Moore-Harrison, T.L., Lightfoot, J.T. (2012). Effects of supraphysiological doses of sex steroids on wheel running activity in mice. Journal of Steroids and Hormonal Science. 3:110
Knab, A.M., Bowen, R.S., Hamilton, A.T., Lightfoot, J.T. (2012) Pharmacological manipulation of the dopaminergic system affects wheel-running activity in differentially active mice. Journal of Biological Regulators and Homeostatic Agents. 26(1): 119-129
Bowen, R.S., Ferguson, D.P., Lightfoot, J.T. (2011) Effects of aromatase inhibition on the physical activity levels of male mice. Journal of Steroids and Hormonal Science. S1:001
*Bowen, RS, MJ Turner, JT Lightfoot. Sex Hormone Effects on Physical Activity Levels: Why Doesn't Jane Run as much as Dick? Sports Medicine 41 (1): 73:86, 2011
Ferguson, DP, RS Bowen, JT Lightfoot. Heart rate and core temperature responses of elite pit crews during automobile races. Journal of Strength and Conditioning Research. 2011. 25(8): 2075-2083
Leamy, LJ, D. Pomp, JT Lightfoot. Epistatic interactions of genes influence within-individual variation of physical activity traits in mice. Genetica. 2011. 139:813-821
Lightfoot, JT. Current Understanding of the Genetic Basis for Physical Activity. Journal of Nutrition. 2011. 141:526-530
Jung, AP, *TS Curtis, MJ Turner, JT Lightfoot. Physical Activity and Food Consumption in High- and Low-Active Inbred Mouse Strains. Med Sci Sports Exerc. 42(10):1826-1833 2010
*Knab, AM, JT Lightfoot. Does the difference between physically active and couch potato lie in the dopamine system? International Journal of Biological Sciences. 6:133-150, 2010
Leamy, LJ, D Pomp, JT Lightfoot. A search for quantitative trait loci controlling within-individual variation of physical activity traits in mice. BMC Genetics. 11:83. 2010
Lightfoot, JT, L Leamy, D Pomp, MJ. Turner, AA.Fodor, *A Knab, *RS Bowen, *D Ferguson, *T Moore-Harrison, A Hamilton. Strain Screen and Haplotype Association Mapping of Wheel Running in Inbred Mouse Strains. J Appl Physiol. 109: 623-634
Other Publications and Presentations
Vellers, HL, SR Kleeberger, JT Lightfoot. Inter-individual Variation in Adaptations to Endurance and Resistance Exercise Training: Genetic Approaches Towards Understanding a Complex Phenotype. Mammalian Genome. 29(1-2), 48-62, 2018. https://doi.org/10.1007/s00335-017-9732-5
Bamman, MM, DM Cooper, FW Booth, ER Chin, PD Neufer, S Trappe, JT Lightfoot, WE Kraus, MJ Joyner. (2014) Exercise Biology and Medicine: Innovative Research to Improve Global Health. Mayo Clinic Proc. 89(2):148-153.
RESEARCH PROJECTS
Mechanisms of Maternal Programming to Offset Cardiac Impairment caused by Early Life Growth Restriction
PI. Michigan State University - NIH (Federal)
2020-04-01 — 2022-03-31
Texas A&M Center for Environmental Health Research
Co-I. National Institutes of Health (DHHS/PHS/NIH) (Federal)
2019-04-01 — 2024-03-31
Metabolic Phenotyping Using Kinetic Measurements in High-and Low-Active Mice
PI. American College of Sports Medicine (Private)
2018-02-01 — 2019-03-02
The MENTORS (Model Education Networks to Optimize Rural Science) Project
PI. Texas A&M University Health Science Center - NIH (Federal)
2016-08-15 — 2021-07-31
Physical Activity Impacts of a Planned Activity-Friendly Community: The What, Where, When and Why of Environmental Approaches to Obesity Prevention
Co-I. Texas A&M University Health Science Center - NIH (Federal)
2015-09-25 — 2020-08-31
(STUDENT GRANT - HEATHER VELLERS) The Effect of Chronic Overfeeding on Voluntary Physcial Activity
PI. American College of Sports Medicine Foundation (Private)
2015-07-01 — 2016-06-30
PESCA: Nox2 Regulation in the Diaphragm Muscle with Duchenne Muscular Dystrophy
Co-PI (). TAMU Office of the Vice President for Research - PESCA (State)
2015-05-01 — 2016-04-30
NIH Proposed Program Project Grant (P01)
PI. TAMU Office of the Vice President for Research (State)
2015-02-01 — 2017-01-31
Genetic, Environmental and Behavioral Determinants of Obesity in Mexican American Children Living Along the Houston Ship Channel
PI. Texas A&M University Health Science Center (State)
2013-12-01 — 2018-11-30
Undoing the Damage: Reprogramming the effects of early high sugar/high fat diets through exercise
PI. DOD-Army Medical Research Acquisition Activity (Federal)
2013-09-15 — 2017-03-14
Peripheral Skeletal Muscle Mechanisms Regulating Voluntary Physical Activity
PI. DHHS-PHS-NIH (Federal)
2013-09-01 — 2018-08-31
Peripheral Skeletal Muscle Mechanisms Regulating Voluntary Physical Activity
PI. DHHS-PHS-NIH (Federal)
2012-09-01 — 2017-08-31
Genetic Mechanisms Regulating Physical Activity Behavior in Mice
PI. DHHS-PHS-NIH (Federal)
2012-07-01 — 2017-06-30
Hypothalamic Inflammation and Exercise: Transcriptional Mechanisms and Targets
PI. Virginia Polytechnic Institution and State University (State)
2012-04-01 — 2017-03-31
Genetic Basis for Exercise Performance: Responses to Exercise Training
Co-I (). DOD-Army-Medical Research and Development Command (Federal)
2011-12-01 — 2015-11-30
Biological Factors Controlling Physical Activity Behavior
PI. DHHS-PHS-NIH (Federal)
2011-07-01 — 2016-06-30
Hypothalamic Inflammation and Exercise: Transcriptional Mechanisms and Targets
PI. Virginia Polytechnic Institution and State University (State)
2011-07-01 — 2016-06-30
Genetic Factors Responsible for Maximal Exercise Endurance
PI. DHHS-PHS-NIH-NIAMSD (Federal)
2010-08-01 — 2011-07-30
AWARDS
AFS College Level Teaching Award (2017)
AFS University Mentoring Award (2018)
Pease Family Scholar at Iowa State University. Pease Family Scholar at Iowa State University (this is a national research-based award). (2017)
EDITORSHIPS
Associate Editor. Medicine and Science in Sports and Exercise (2015)
LEADERSHIP POSITIONS
Chair. Distinguished Faculty in Aging Search Committee. (2011)
Chair. Heldenfels Lab Renovation Committee. (2011)
Chair. HLKN Tenure and Promotion Committee. (2014)