Director Center for Translational Research Aging, Health and Kinesiology
Office#: 125 Human Clinical Research Facility
Mail Stop: 4253
Office Phone: (979) 220-2910
Other Title: Ponder Endowed Chair
Directory Title: Director Center for Translational Research Aging
Primary Emphasis Area: Kinesiology
Vita: View Document
Google Scholar: Google Scholar Profile
Short Bio
Experience : Dr. Nicolaas Deutz, MD, PhD currently serves as Director for the Center for Translational Research in Aging and Longevity (CTRAL). For more than 30 years, his research background and expertise focus on nutrition, metabolism, and physiology studies involving the use of stable isotope methodologies, both in humans and animals. Dr. Deutz has extensive experience with isotopic calculations, validation and data interpretation. The stable isotope approaches are used in several studies to unravel the metabolic changes in patients with chronic diseases (i.e., chronic obstructive pulmonary disease, cancer, cystic fibrosis, chronic heart failure, obstructive sleep apnea, mild cognitive impairment and dementia, autism spectrum disorder). This research leads to new insights in protein and amino acid kinetics in subjects with chronic disease and resulted in specific recommendations to nutritional supplements as method for reducing muscle wasting. Recently, he started studying the anabolic effects of specialized nutritional supplements in different chronic diseases and models of disease. Using translational approaches is a logical extension of the body of his research in the field of protein and amino acids metabolism. Education: Dr. Deutz obtained his MD and PhD at the University of Amsterdam, Netherlands. He is a medical physiologist and Nutrition Physician Specialist. Learn more about Dr. Deutz by visiting his page on CTRAL's website
Research Interests
amino acids
chroninc disease
clinical nutrition
older adults
Publications (journal articles, books, book chapters)*

1. Jonker R, Deutz NEP, Harrykissoon R, Zachria AJ, Veley EA, Engelen M. A critical evaluation of the anabolic response after bolus or continuous feeding in COPD and healthy older adults. Clin Sci (Lond). 2018;132(1):17-31. Epub 2017/12/01. doi: 10.1042/CS20171068. PubMed PMID: 29187513.

2. Jonker R., Deutz N.E.P., Harrykissoon R., Zachria A.J., Veley E.A., Engelen M.P.K.J. A critical evaluation of the anabolic response after bolus or continuous feeding in COPD and healthy older adults. Clinical Science. 2018: 132:17-31

3. Van der Meij B.S., Teleni L, Engelen M.P.K.J., Deutz N.E.P. Amino Acid Kinetics and the Response to Nutrition in Patients with Cancer. International Journal of Radiation Biology 2018: 3:1-13

4. van der Meij BS, Teleni L, Engelen M, Deutz NEP. Amino acid kinetics and the response to nutrition in patients with cancer. International journal of radiation biology. 2018:1-13. Epub 2018/04/19. doi: 10.1080/09553002.2018.1466209. PubMed PMID: 29667485.

5. Barnes RC, Kim H, Fang C, Bennett W, Nemec M, Sirven MA, Suchodolski JS, Deutz N, Britton RA, Mertens-Talcott SU, Talcott ST. Body Mass Index as a Determinant of Systemic Exposure to Gallotannin Metabolites during 6-Week Consumption of Mango (Mangifera indica L.) and Modulation of Intestinal Microbiota in Lean and Obese Individuals. Molecular nutrition & food research. 2018;0(ja):e1800512. Epub 2018/11/15. doi: 10.1002/mnfr.201800512. PubMed PMID: 30427574.

6. Ten Have GAM, Deutz RCI, Engelen M, Wolfe RR, Deutz NEP. Characteristics of a Pseudomonas aeruginosa induced porcine sepsis model for multi-organ metabolic flux measurements. Lab Anim. 2018;52(2):163-75. Epub 2017/07/07. doi: 10.1177/0023677217718003. PubMed PMID: 28679339.

7. van Zwol A, Oosterloo NBC, de Betue CT, Bogers A, de L, II, Deutz NEP, Joosten KFM. Effects of glucocorticoids on serum amino acid levels during cardiac surgery in children. Clin Nutr ESPEN. 2018;23:212-6. Epub 2018/02/21. doi: 10.1016/j.clnesp.2017.09.012. PubMed PMID: 29460801

8. Prado CM, Purcell SA, Alish C, Pereira SL, Deutz NE, Heyland DK, Goodpaster BH, Tappenden KA, Heymsfield SB. Implications of low muscle mass across the continuum of care: a narrative review. Annals of medicine. 2018:1-19. Epub 2018/09/01. doi: 10.1080/07853890.2018.1511918. PubMed PMID: 30169116.

9. Lieben CK, Blokland A, Deutz NE, Jansen W, Han G, Hupperts RM. Intake of tryptophan-enriched whey protein acutely enhances recall of positive loaded words in patients with multiple sclerosis. Clin Nutr. 2018;37(1):321-8. Epub 2017/02/06. doi: 10.1016/j.clnu.2016.12.029. PubMed PMID: 28153503.

10. Engelen M, Deutz NEP. Is beta-hydroxy beta-methylbutyrate an effective anabolic agent to improve outcome in older diseased populations? Curr Opin Clin Nutr Metab Care. 2018;21(3):207-13. Epub 2018/02/07. doi: 10.1097/MCO.0000000000000459. PubMed PMID: 29406417; PMCID: PMC5882564.

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* Publication was joint-authored with students
Diss Publication was from a dissertation
ROS Publication was from a record of study

College of Education and Human Development Grants and Contracts (Current)

Catapult #5. (PI)
2018/11/01 - 2020/05/01
Total Funding: .

Engineering Research Center for Precise Advanced Technologies andHealth Systems for Underserved Populations (PATHS-UP). (Co-PI)
National Science Foundation (Federal)
2017/08/01 - 2022/07/31
Total Funding: 28,545.

Nutrition and Exercise in Critical Illness (The NEXIS Trial): A Randomized Trail of Combined Cycle Ergometry and Amino Acids in the ICU. (PI)
University of Vermont - NIH (Federal)
2017/04/01 - 2022/03/31
Total Funding: 112,697.
Courses Taught
2019 - 2020
KINE 690
2018 - 2019
KINE 690
2012 - 2013
KINE 685
Editorial Positions

Assoc Editor (2014 - ). Clinical Nutrition Experimental

Editorial Board Member (2008 - ). American Journal of Physiology: Endocrinology and Metabolism

Editor (2005 - ). Clinical Nutrition

Editor (2005 - ). e-SPEN, the European e-Journal of Clinical Nutrition and Metabolism;


(2013-2013). ESPEN Followship.  Effect of enteral nutritional intervention on glutathione metabolism during Pseudomonas aeruginosa induced sepsis in the pig

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