Directory » CHRISTOPHER WOODMAN
311
845-0515
Dr. Woodman received a Ph.D. in Physiological Sciences from the University of Arizona under the mentorship of Dr. Charles Tipton. After graduate school he moved to the University of Missouri to complete a post-doctoral fellowship with Dr. Harold Laughlin in the Department of Biomedical Sciences. He joined the faculty in the Department of Health and Kinesiology at Texas A&M in 2006 where he is currently an Associate Professor and Director of the Vascular Biology Laboratory. His research focuses on the interactive effects of aging and exercise training on skeletal muscle vascular beds. The mission of the Vascular Biology Laboratory is to understand how the structure and function of arteries change with age and how these changes increase cardiovascular disease risk in the elderly. In addition, the laboratory seeks to determine mechanisms by which exercise training attenuates, or reverses, the detrimental effects of aging on vascular function. Dr. Woodman has received research support from the National Institutes of Health and the American Heart Association.
Education
Ph.D., Physiological Sciences, University of Arizona (1995)
M.S., Exercise Science, University of Arizona (1989)
B.A., Biology, Colgate University (1986)
COURSES TAUGHT
KINE386. SPORT PHYSIOLOGY
2015A
KINE433. PHYSIOLOGY OF EXERCISE
2021C,2021A2020C,2020A,2019C,2019A,2018C
KINE485. Directed Studies
2006C
KINE491. RESEARCH
2013A
KINE626. Exercise Clin Population
2009A,2008A
KINE626. EXERCISE CLIN POPULATION
2021A,2020A,2019A,2018A,2017A,2016A
KINE638. EXERCISE PHYSIOLOGY II
2020C,2019C,2018C,2017C,2016C
KINE638. Exercise Physiology II
2008C,2007C,2006C
KINE681. SEMINAR
2016C,2012C
KINE681. Seminar
2008A
KINE683. PRACTICUM IN KINESIOLOGY
2015C
KINE684. PROF INTERNSHIP
2016C,2015C,2015A,2012C
KINE685. Directed Studies
2009B,2008C,2007A,2006C,2006B
KINE685. DIRECTED STUDIES
2020C,2018C,2018A,2017C,2016C
KINE689. Special Topics In Ad Cardio Physiolgy
2008A,2007A
FORMER DOCTORAL STUDENTS
Dylan Holly, Ph.D. (2022)
Song Yi Shin, Ph.D. (2022)
John Seawright, Ph.D. (2016)
Meredith Luttrell, Ph.D. (2014)
Daniel Trott, Ph.D. (2010)
SELECTED PUBLICATIONS
Books and Monographs
Journal Articles
Holly, D., Kim, H., Woodman, C.R., and Massett, M.P. (2023). Genetic background influences arterial vasomotor function in male and female mice. Physiol. Rep. 11: e15824. [published with student]
Ojha, K.R., Shin, S.Y., Padgham, S., Olmedo, F.L., Guo, B., Han, G., Woodman, C.R., and Trache, A. (2022). Age-associated dysregulation on integrin function in vascular smooth muscle. Front. Physiol. 13: 1-15. [published with student]
Trache, A, Massett, M.P., and Woodman, C.R. (2020). Vascular smooth muscle stiffness and its role in aging. Curr. Top. Membr. 86: 217-253.
Luttrell, M., Kim, H., Shin, S.Y., Holly, D., Massett, M., and Woodman, C.R. (2019). Heterogeneous effect of aging on vasorelaxation responses in large and small arteries. Physiol. Rep. 7: e1431. DOI: 10.14814/phy2.14341 [published with student]
Coletta, A.M., Sanchez, B., O'Connor, A., Dalton, R., Springer, S., Koozehchian, M.S., Murano, P.S., Woodman, C.R., Rasmussen, C., and Kreider, R.B. (2018). Alignment of diet prescription to genotype does not promote greater weight loss success in women with obesity participating in an exercise and weight loss program. 4: 554-574. [published with student]
Joubert, D.P., Granados, J.Z., Oliver, J.M., Noack, B.L., Grandjean, P.W., Woodman, C.R., Riechman, S.E., and Crouse, S.F. (2018). An acute bout of aquatic treadmill exercise induces greater improvements in endothelial function and post-exercise hypotension than land treadmill exercise: a crossover design. Am. J. Phys. Med. Rehabil. 97: 578-584 [published with student]
Seawright, J.W., Sreenivasappa, H., Gibbs, H.C., Padgham, S., Shin, S.Y., Chaponnier, C., Yeh, A.T., Trzeciakowski, J.P., Woodman, C.R., and Trache, A. (2018). Vascular smooth muscle contractile function declines with age in skeletal muscle feed arteries. Front. Physiol. 9: 1-12. [published with student]
Woodman, C.R., Seawright, J.W., Luttrell, M.J., Shin, S.Y., and Trache, A. (2018). Importance of mechanical signals in promoting exercise-induced improvements in vasomotor function of aged skeletal muscle resistance arteries. Am. J. Physiol. Heart Circ. 315: H602-H609. [published with student]
Seawright, J.W., Luttrell, M.J., Trache, A., and Woodman, C.R. (2016). Short-term increases in pressure and shear stress attenuate age-related declines in endothelial function in skeletal muscle feed arteries. Eur. J. Appl. Physiol. 116: 1305-1311 [published with student]
Seawright, J.W., Trache, A., Wilson E., and Woodman, C.R. (2016). Short-duration increases in intraluminal pressure improve improve vasoconstrictor responses in aged skeletal muscle feed arteries. Eur. J. Appl. Physiol. 116: 931-937 [published with student]
Seawright, J.W., Luttrell, M.J., and Woodman, C.R. (2014). Acute increases in intraluminal pressure improve vasodilator responses in aged soleus muscle feed arteries. Eur. J. Appl. Physiol. 114: 2213-2221. [published with student]
Luttrell, M.J., Seawright, J.W., Wilson, E, and Woodman, C.R. (2013) Effect of age and exercise training on protein:protein interactions among eNOS and its regulatory proteins in rat aortas. Eur. J. Appl. Physiol. 113: 2761-2768 [published with student]
Trott, D.W., Luttrell, M.J., Seawright, J.W., and Woodman, C.R. (2013). Aging impairs PI3K/Akt signaling and NO-mediated dilation in soleus muscle feed arteries. Eur. J. Appl. Physiol. 113:2039-2046 [published with student]
Trott, D.W., Seawright, J.W. Luttrell, M.L. and Woodman, C.R. (2011). NADPH oxidase derived reactive oxygen species contribute to age related impairments of endothelium dependent dilation in rat soleus feed arteries. J. Appl. Physiol. 110: 1171-1180, 2011 [published with student]
Trott, D.W., Gunduz, F., Laughlin, M.H., and Woodman, C.R. (2009). Exercise training increases ecSOD protein content and reverses age-related decrements in endothelium-dependent dilation in soleus feed arteries. J. Appl. Physiol. [published with student]
Woodman,C.R. (2009) Setting the tone for aging in the skeletal muscle vasculature. J. Appl. Physiol.
Lesniewski LA, Donato AJ, Behnke BJ, Woodman CR, Laughlin MH, Ray CA, and Delp MD. Decreased NO signaling leads to enhanced vasoconstrictor responsiveness in skeletal muscle arterioles of the ZDF rat prior to overt diabetes and hypertension. Am J Physiol Heart Circ Physiol 294: H1840-H1850, 2008.
Woodman CR, Trott DW, and Laughlin MH. Short-term increases in intraluminal pressure reverse age-related decrements in endothelium-dependent dilation in soleus muscle feed arteries. J Appl Physiol 103: 1172-1179, 2007. [published with student]
Woodman CR, Ingram D, Bonagura J, and Laughlin MH (2006). Exercise training improves femoral artery blood flow responses to endothelium-dependent dilators in hypercholesterolemic pigs. Am. J. Physiol. 290: H2362-H2368.
Woodman CR, Price EM, and Laughlin MH. Shear stress induces eNOS mRNA expression and improves endothelium-dependent dilation in senescent soleus feed arteries. J Appl Physiol 98: 940-946, 2005.
Woodman, CR, Thompson MA, Turk JR and Laughlin MH. (2005). Endurance exercise training improves endothelium-dependent relaxation in brachial arteries from hypercholesterolemic male pigs. J. Appl Physiol 99: 1412-1421.
Laughlin, M.H., Woodman, C.R., Schrage, W.G., Gute, D. & Price, E.M. (2004). Interval sprint training enhances endothelial function in some arteries that perfuse white gastrocnemius muscle. Journal of Applied Physiology 96:233-244.
Thompson, M.A., Henderson, K.K., Woodman, C.R., Turk, J.R., Rush, J.W.E., Price, E.M., & Laughlin, M.H. (2004). Exercise preserves endothelium-dependent relaxation in coronary arteries from hypercholesterolemic male pigs. Journal of Applied Physiology 96:1114-1126.
Woodman, C.R., Turk, J.R., Rush, J.W.E., & Laughlin, M.H. (2004). Exercise attenuates the effects of hypercholesterolemia on endothelium-dependent relaxation in porcine coronary arteries. Journal of Applied Physiology 96: 1105-1113.
Laughlin, M.H., Rubin, L.J., Rush, J.W.E., Price, E.M., Schrage, W.G., & Woodman, C.R. (2003). Short-term training increases endothelium-dependent relaxation in conduit coronary arteries, not coronary arterioles. Journal of Applied Physiology 94:234-244.
Laughlin, M.H., Turk, J.R., Schrage, W.G., Woodman, C.R., & Price, E.M. (2003). Influence f coronary artery diameter on eNOS protein content. American Journal of Physiology 284: H1307-H1312.
Woodman, C.R., Price, E.M., & Laughlin, M.H. (2003). Aging impairs nitric oxide-and prostacyclinmediation of endothelium-dependent dilation in soleus feed arteries. Journal of Applied Physiology 95:2164-2170.
Woodman, C.R., Turk, J.R., Williams, D.P., & Laughlin, M.H. (2003). Exercise training preserves endothelium-dependent relaxation in brachial arteries from hyperlipidemic pigs. Journal of Applied Physiology 94:2017-2026.
Schrage, W.G., Woodman, C.R., & Laughlin, M.H. (2002). Mechanisms of flow and Ach-induced dilation in rat soleus arterioles are altered by hindlimb unweighting. Journal of Applied Physiology 92:901-911.
Woodman, C.R., Price, E.M., & Laughlin, M.H. (2002). Aging induces muscle specific impairment of endothelium-dependent dilation in skeletal muscle feed arteries. Journal of Applied Physiology 93: 1685-1690.
Griffin, K.G., Woodman, C.R., Price, E.M., Laughlin, M.H., & Parker, J.L. (2001). Endothelium-mediated relaxation of porcine collateral-dependent arterioles is imporved by exercise training. Circulation 104:1393-1398.
Laughlin, M.H., Pollock, J.S., Amann, J.F., Hollis, M.L., Woodman, C.R. & Price, E.M. (2001). Training induced increases in ecNOS expression are distributed heterogeneously in the coronary arterial tree. Journal of Applied Physiology 90:501-510.
Woodman, C.R., Schrage, W.G., Rush, J.W.E., Price, E.M., Hasser, E.M. & Laughlin, M.H. (2001). Hindlimb unweighting devreases endothelium dependent dilation and eNOS expression in soleus not gastrocnemius. Journal of Applied Physiology 91:1091-1098.
Bowles, D.K., Woodman, C.R., & Laughlin, M.H. (2000).Coronary smooth muscle and endothelial adaptations to exercise training. Exercise Sport Science Review 28: 57-62.
Rush, J.W.E., Laughlin, M.H., Woodman, C.R., & Price, E.M. (2000). SOD-1 expression in pig coronary arterioles is increased by training. American Journal of Physiology 279: H2068-H2076.
Schrage, W.G., Woodman, C.R., & Laughlin, M.H.. (2000). Hindlimb unweighting alters endothelium-dependent vasodilation and ecNOS expression insoleus arterioles. Joural of Applied Physiology 89: 1483-1490.
Jasperse, J.L., Woodman, C.R., Price, E.M., Hasser, E.M., Laughlin, M.H. (1999). Hindlimb unweighting decreases ecNOS gene expression and endothelium-dependent dilation in rat soleus feed arteries. Journal of Applied Physiology 87:1476-1482.
Woodman, C.R., Muller, J.M., Rush, J.W.E., Laughlin, M.H., & Price, E.M. (1999). Flow regulation of ecNOS and Cu/Zn SOD mRNA expression in porcine coronary arterioles. American Journal of Physiology 276: H1058-1063.
Book Chapters
Rush JWE, Woodman CR, Aaker AA, Schrage WG, and Laughlin MH. Skeletal muscle blood flow and endurance exercise. In: Endurance in Sport. R.J. Shepard and P.O. Astrand (Eds.). Blackwell Science, Oxford, 2000; 84-117.
RESEARCH PROJECTS
T3 - Cell Stiffness in Vascular Disease
Integrins as Regulators of Vascular Contractility in Aged Resistance Arteries
T3 - Influence of Genetic Background on Vascular Function
Aging of Vascular Smooth Muscle in Resistance Arteries
Aging of Vascular Smooth Muscle in Resistance Arteries
Functional and Structural Alterations in Aged Vascular Smooth Muscle Cells
Post-translational Mechanisms Regulating eNOS Function and Endothelium-Dependent Dilation in Senescent Skeletal Muscle Resistance Vessels
Functional and Structural Alterations in Aged Vascular Smooth Muscle Cells
Exercise Training Reverses Age-related Endothelial Dysfunction: Role of Shear Stress
Shear Stress and Pressure Regulation of Endothelial Function in Senescent Coronary Arterioles
Exercise Training Reverses Age-related Endothelial Dysfunction: Role of Shear Stress
Simulated Microgravity Regulation of Endothelial Pheonotype
Vascular Biology and Aging: Modulation of Endothelial Phenotype by Pressure and Shear Stress
Aging: Modulation of Endothelial Phenotyped by Pressure and Shear Stress
Vascular Function: Aging and Regulation of NO-bioavailability
Vascular Biology and Aging: Modulation of Endothelial Cell Phenotype by Pressure and Shear Stress
Aging: Modulation of Endothelial Phenotype by Pressure and Shear Stress
Aging: Modulation of Endothelial Phenotype by Pressure and Shear Stress
Caveolin Regulation of eNOS: Effects of Aging and Exercise
Vascular Biology and Aging: Mechanisms of Endothelial Dysfunction
Age, Exercise, and Endothelial Function
Vascular Biology and Aging: Mechanisms of Endothelial Dysfunction
Vascular Biology: Aging and Endothelial Dysfunction
AWARDS
Association of Former Students Distinguished Teaching Award - College Level (2021)
Collins Faculty Fellow (2011)
Editors Choice Award. Journal of Applied Physiology. (2011)
Graduate Academic Scholarship. University of Arizona. (1992)
National Research Service Award. National Institutes of Health. (1997)
Research Career Development Award. National Institutes of Health. (2001)
"Star Reviewer". Journal of Applied Physiology. (2010)
EDITORSHIPS
Associate Editor. Exercise and Sport Sciences Reviews (2013-2014)
Editorial Board Member. Frontiers in Vascular Physiology (2011-present)
Editorial Board Member. Journal of Applied Physiology (2009-present)