Directory » YUMING LEI
328
862-3392
My scientific interests focus on studying how the brain controls movements in individuals with and without neurological disorders. Specifically, I am interested in investigating neural mechanisms of motor control and learning, modulation in cortical circuits, and neuroplasticity by employing biomechanical techniques, robotics, non-invasive brain stimulation, electrophysiology, and neuroimaging.
SELECTED PUBLICATIONS
Journal Articles
1. Bao, S., Kim, H., Shettigar, N. B., Li, Y., & Lei, Y. (2024). Personalized depth-specific neuromodulation of the human primary motor cortex via ultrasound. The Journal of Physiology, 602:933-948. doi: 10.1113/JP285613
2. Bao, S., Wang, Y., Escalante, Y. R., Li, Y., & Lei, Y. (2024) Modulation of motor cortical inhibition and facilitation by touch sensation from the glabrous skin of the human hand. eNeuro, 11. DOI: https://doi.org/10.1523/ENEURO
3. Wang, Y., Huynh, A. T., Bao, S., Buchanan, J. J., Wright, D. L., & Lei, Y. (2024). Memory consolidation of sequence learning and dynamic adaptation during wakefulness. Cerebral Cortex, bhad507. https://doi.org/10.1093/cercor/bhad507
4. Bao, S., & Lei, Y. (2024). Motor unit activity and synaptic inputs to motoneurons in the caudal part of the injured spinal cord. Journal of Neurophysiology, 131:187–197. https://doi.org/10.1152/jn.00178.2023
5. Rizvi, A., Bell, K., Yang, D., Montenegro, M. P., Kim, H., Bao, S., ... & Lei, Y. (2023). Effects of transcranial direct current stimulation over human motor cortex on cognitive-motor and sensory-motor functions. Scientific Reports, 13:20968. https://doi.org/10.1038/s41598-023-48070-z
6. Lei, Y., Rios, V., Ji, J., Duhon, B., Boyd, H., & Xu, Y. (2023). Quantifying unsupported sitting posture impairments in humans with cervical spinal cord injury using a head-mounted IMU sensor. Spinal Cord, 1-6. https://doi.org/10.1038/s41393-023-00951-w
7. Escalante, Y. R., & Lei, Y. (2023). Insights into motor memory interference among experts and competent individuals. Journal of Neurophysiology, 129:1225-1227. https://doi.org/10.1152/jn.00523.2022
8. Bao, S., & Lei, Y. (2022). Memory decay and generalization following distinct motor learning mechanisms. Journal of Neurophysiology, 128:1534-1545. https://doi.org/10.1152/jn.00105.2022
9. Bao, S., Wang, Y., Wright, D. L., Buchanan, J. J., & Lei, Y. (2022). Differences in motor unit recruitment patterns and low frequency oscillation of discharge rates between unilateral and bilateral isometric muscle contractions. Human Movement Science, 83:102952. https://doi.org/10.1016/j.humov.2022.102952
10. Davis, M., Wang, Y., Bao, S., Buchanan, J. J., Wright, D. L., & Lei, Y. (2022). The interactions between primary somatosensory and motor cortex during human grasping behaviors. Neuroscience, 485:1-11. https://doi.org/10.1016/j.neuroscience.2021.11.039
11. Bao, S., Wang, J., Wright, D. L., Buchanan, J. J., & Lei, Y. (2022). The decay and consolidation of effector-independent motor memories. Scientific Reports, 12:3131. https://doi.org/10.1038/s41598-022-07032-7
12. Bao, S., Lei, Y., Keenan, K. G., & Wang, J. (2022). Generalization of visuomotor adaptation associated with use-dependent learning across different movement workspaces and limb postures. Human Movement Science, 86:103017. https://doi.org/10.1016/j.humov.2022.103017
13. Lei, Y., & Perez, M. A. (2021). Cerebellar contribution to sensorimotor adaptation deficits in humans with spinal cord injury. Scientific Reports, 11:2507. https://doi.org/10.1038/s41598-020-77543-8
14. Christiansen, L., Chen, B., Lei, Y., Urbin, M. A., Richardson, M. S., Oudega, M., ... & Perez, M. A. (2021). Acute intermittent hypoxia boosts spinal plasticity in humans with tetraplegia. Experimental Neurology, 335:113483. https://doi.org/10.1016/j.expneurol.2020.113483
15. Bao, S., Morgan, A. M., Lei, Y., & Wang, J. (2020). Lack of interlimb transfer following visuomotor adaptation in a person with congenital mirror movements. Neuropsychologia, 136:107265. https://doi.org/10.1016/j.neuropsychologia.2019.107265
16. Lei, Y., Akbar, A., & Wang, J. (2019). Direct-effects and after-effects of dynamic adaptation on intralimb and interlimb transfer. Human Movement Science, 65:102-110. https://doi.org/10.1016/j.humov.2018.05.014
17. Lei, Y., Ozdemir, R. A., & Perez, M. A. (2018). Gating of sensory input at subcortical and cortical levels during grasping in humans. Journal of Neuroscience, 38:7237-7247. https://doi.org/10.1523/JNEUROSCI.0545-18.2018
18. Lei, Y., & Perez, M. A. (2018). Phase-dependent deficits during reach-to-grasp after human spinal cord injury. Journal of Neurophysiology, 119:251-261. https://doi.org/10.1152/jn.00542.2017
19. Hodkin, E. F., Lei, Y., Humby, J., Glover, I. S., Choudhury, S., Kumar, H., ... & Jackson, A. (2018). Automated FES for upper limb rehabilitation following stroke and spinal cord injury. IEEE Transactions on Neural Systems and Rehabilitation Engineering, 26:1067-1074. https://doi.org/10.1109/TNSRE.2018.2816238
20. Lei, Y., & Wang, J. (2018). The effect of proprioceptive acuity variability on motor adaptation in older adults. Experimental Brain Research, 236:599-608. https://doi.org/10.1007/s00221-017-5150-x
21. Lei, Y., Suresh, N. L., Rymer, W. Z., & Hu, X. (2018). Organization of the motor‐unit pool for different directions of isometric contraction of the first dorsal interosseous muscle. Muscle & Nerve, 57:E85-E93. https://doi.org/10.1002/mus.25963
22. Lei, Y., & Perez, M. A. (2017). Cortical contributions to sensory gating in the ipsilateral somatosensory cortex during voluntary activity. The Journal of Physiology, 595: 6203-6217. https://doi.org/10.1113/JP274504
23. Lei, Y., Bao, S., Perez, M. A., & Wang, J. (2017). Enhancing generalization of visuomotor adaptation by inducing use-dependent learning. Neuroscience, 366:184-195. https://doi.org/10.1016/j.neuroscience.2017.10.004
24. Bao, S., Lei, Y., & Wang, J. (2017). Experiencing a reaching task passively with one arm while adapting to a visuomotor rotation with the other can lead to substantial transfer of motor learning across the arms. Neuroscience Letters, 638:109-113. https://doi.org/10.1016/j.neulet.2016.12.028
25. Lei, Y., Bao, S., & Wang, J. (2016). The combined effects of action observation and passive proprioceptive training on adaptive motor learning. Neuroscience, 331:91-98. https://doi.org/10.1016/j.neuroscience.2016.06.011
26. Wang, J., & Lei, Y. (2015). Direct-effects and after-effects of visuomotor adaptation with one arm on subsequent performance with the other arm. Journal of Neurophysiology, 114:468-473. https://doi.org/10.1152/jn.00298.2015
27. Wang, J., Lei, Y., & Binder, J. R. (2015). Performing a reaching task with one arm while adapting to a visuomotor rotation with the other can lead to complete transfer of motor learning across the arms. Journal of Neurophysiology, 113:2302-2308. https://doi.org/10.1152/jn.00974.2014
28. Lei, Y., & Wang, J. (2014). Prolonged training does not result in a greater extent of interlimb transfer following visuomotor adaptation. Brain and Cognition, 91:95-99. https://doi.org/10.1016/j.bandc.2014.09.004
29. Lei, Y., Johnson, M. J., & Wang, J. (2013). Separation of visual and motor workspaces during targeted reaching results in limited generalization of visuomotor adaptation. Neuroscience Letters, 541:243-247. https://doi.org/10.1016/j.neulet.2013.02.045
30. Wang, J., Lei, Y., Xiong, K., & Marek, K. (2013). Substantial generalization of sensorimotor learning from bilateral to unilateral movement conditions. PLoS One, 8:e58495. https://doi.org/10.1371/journal.pone.0058495
31. Wagner-Schuman, M., Dubis, A. M., Nordgren, R. N., Lei, Y., Odell, D., Chiao, H., ... & Carroll, J. (2011). Race-and sex-related differences in retinal thickness and foveal pit morphology. Investigative Ophthalmology & Visual Science, 52:625-634. https://doi.org/10.1167/iovs.10-5886
32. Wang, J., Joshi, M., & Lei, Y. (2011). The extent of interlimb transfer following adaptation to a novel visuomotor condition does not depend on awareness of the condition. Journal of Neurophysiology, 106:259-264. https://doi.org/10.1152/jn.00254.2011
2. Bao, S., Wang, Y., Escalante, Y. R., Li, Y., & Lei, Y. (2024) Modulation of motor cortical inhibition and facilitation by touch sensation from the glabrous skin of the human hand. eNeuro, 11. DOI: https://doi.org/10.1523/ENEURO
3. Wang, Y., Huynh, A. T., Bao, S., Buchanan, J. J., Wright, D. L., & Lei, Y. (2024). Memory consolidation of sequence learning and dynamic adaptation during wakefulness. Cerebral Cortex, bhad507. https://doi.org/10.1093/cercor/bhad507
4. Bao, S., & Lei, Y. (2024). Motor unit activity and synaptic inputs to motoneurons in the caudal part of the injured spinal cord. Journal of Neurophysiology, 131:187–197. https://doi.org/10.1152/jn.00178.2023
5. Rizvi, A., Bell, K., Yang, D., Montenegro, M. P., Kim, H., Bao, S., ... & Lei, Y. (2023). Effects of transcranial direct current stimulation over human motor cortex on cognitive-motor and sensory-motor functions. Scientific Reports, 13:20968. https://doi.org/10.1038/s41598-023-48070-z
6. Lei, Y., Rios, V., Ji, J., Duhon, B., Boyd, H., & Xu, Y. (2023). Quantifying unsupported sitting posture impairments in humans with cervical spinal cord injury using a head-mounted IMU sensor. Spinal Cord, 1-6. https://doi.org/10.1038/s41393-023-00951-w
7. Escalante, Y. R., & Lei, Y. (2023). Insights into motor memory interference among experts and competent individuals. Journal of Neurophysiology, 129:1225-1227. https://doi.org/10.1152/jn.00523.2022
8. Bao, S., & Lei, Y. (2022). Memory decay and generalization following distinct motor learning mechanisms. Journal of Neurophysiology, 128:1534-1545. https://doi.org/10.1152/jn.00105.2022
9. Bao, S., Wang, Y., Wright, D. L., Buchanan, J. J., & Lei, Y. (2022). Differences in motor unit recruitment patterns and low frequency oscillation of discharge rates between unilateral and bilateral isometric muscle contractions. Human Movement Science, 83:102952. https://doi.org/10.1016/j.humov.2022.102952
10. Davis, M., Wang, Y., Bao, S., Buchanan, J. J., Wright, D. L., & Lei, Y. (2022). The interactions between primary somatosensory and motor cortex during human grasping behaviors. Neuroscience, 485:1-11. https://doi.org/10.1016/j.neuroscience.2021.11.039
11. Bao, S., Wang, J., Wright, D. L., Buchanan, J. J., & Lei, Y. (2022). The decay and consolidation of effector-independent motor memories. Scientific Reports, 12:3131. https://doi.org/10.1038/s41598-022-07032-7
12. Bao, S., Lei, Y., Keenan, K. G., & Wang, J. (2022). Generalization of visuomotor adaptation associated with use-dependent learning across different movement workspaces and limb postures. Human Movement Science, 86:103017. https://doi.org/10.1016/j.humov.2022.103017
13. Lei, Y., & Perez, M. A. (2021). Cerebellar contribution to sensorimotor adaptation deficits in humans with spinal cord injury. Scientific Reports, 11:2507. https://doi.org/10.1038/s41598-020-77543-8
14. Christiansen, L., Chen, B., Lei, Y., Urbin, M. A., Richardson, M. S., Oudega, M., ... & Perez, M. A. (2021). Acute intermittent hypoxia boosts spinal plasticity in humans with tetraplegia. Experimental Neurology, 335:113483. https://doi.org/10.1016/j.expneurol.2020.113483
15. Bao, S., Morgan, A. M., Lei, Y., & Wang, J. (2020). Lack of interlimb transfer following visuomotor adaptation in a person with congenital mirror movements. Neuropsychologia, 136:107265. https://doi.org/10.1016/j.neuropsychologia.2019.107265
16. Lei, Y., Akbar, A., & Wang, J. (2019). Direct-effects and after-effects of dynamic adaptation on intralimb and interlimb transfer. Human Movement Science, 65:102-110. https://doi.org/10.1016/j.humov.2018.05.014
17. Lei, Y., Ozdemir, R. A., & Perez, M. A. (2018). Gating of sensory input at subcortical and cortical levels during grasping in humans. Journal of Neuroscience, 38:7237-7247. https://doi.org/10.1523/JNEUROSCI.0545-18.2018
18. Lei, Y., & Perez, M. A. (2018). Phase-dependent deficits during reach-to-grasp after human spinal cord injury. Journal of Neurophysiology, 119:251-261. https://doi.org/10.1152/jn.00542.2017
19. Hodkin, E. F., Lei, Y., Humby, J., Glover, I. S., Choudhury, S., Kumar, H., ... & Jackson, A. (2018). Automated FES for upper limb rehabilitation following stroke and spinal cord injury. IEEE Transactions on Neural Systems and Rehabilitation Engineering, 26:1067-1074. https://doi.org/10.1109/TNSRE.2018.2816238
20. Lei, Y., & Wang, J. (2018). The effect of proprioceptive acuity variability on motor adaptation in older adults. Experimental Brain Research, 236:599-608. https://doi.org/10.1007/s00221-017-5150-x
21. Lei, Y., Suresh, N. L., Rymer, W. Z., & Hu, X. (2018). Organization of the motor‐unit pool for different directions of isometric contraction of the first dorsal interosseous muscle. Muscle & Nerve, 57:E85-E93. https://doi.org/10.1002/mus.25963
22. Lei, Y., & Perez, M. A. (2017). Cortical contributions to sensory gating in the ipsilateral somatosensory cortex during voluntary activity. The Journal of Physiology, 595: 6203-6217. https://doi.org/10.1113/JP274504
23. Lei, Y., Bao, S., Perez, M. A., & Wang, J. (2017). Enhancing generalization of visuomotor adaptation by inducing use-dependent learning. Neuroscience, 366:184-195. https://doi.org/10.1016/j.neuroscience.2017.10.004
24. Bao, S., Lei, Y., & Wang, J. (2017). Experiencing a reaching task passively with one arm while adapting to a visuomotor rotation with the other can lead to substantial transfer of motor learning across the arms. Neuroscience Letters, 638:109-113. https://doi.org/10.1016/j.neulet.2016.12.028
25. Lei, Y., Bao, S., & Wang, J. (2016). The combined effects of action observation and passive proprioceptive training on adaptive motor learning. Neuroscience, 331:91-98. https://doi.org/10.1016/j.neuroscience.2016.06.011
26. Wang, J., & Lei, Y. (2015). Direct-effects and after-effects of visuomotor adaptation with one arm on subsequent performance with the other arm. Journal of Neurophysiology, 114:468-473. https://doi.org/10.1152/jn.00298.2015
27. Wang, J., Lei, Y., & Binder, J. R. (2015). Performing a reaching task with one arm while adapting to a visuomotor rotation with the other can lead to complete transfer of motor learning across the arms. Journal of Neurophysiology, 113:2302-2308. https://doi.org/10.1152/jn.00974.2014
28. Lei, Y., & Wang, J. (2014). Prolonged training does not result in a greater extent of interlimb transfer following visuomotor adaptation. Brain and Cognition, 91:95-99. https://doi.org/10.1016/j.bandc.2014.09.004
29. Lei, Y., Johnson, M. J., & Wang, J. (2013). Separation of visual and motor workspaces during targeted reaching results in limited generalization of visuomotor adaptation. Neuroscience Letters, 541:243-247. https://doi.org/10.1016/j.neulet.2013.02.045
30. Wang, J., Lei, Y., Xiong, K., & Marek, K. (2013). Substantial generalization of sensorimotor learning from bilateral to unilateral movement conditions. PLoS One, 8:e58495. https://doi.org/10.1371/journal.pone.0058495
31. Wagner-Schuman, M., Dubis, A. M., Nordgren, R. N., Lei, Y., Odell, D., Chiao, H., ... & Carroll, J. (2011). Race-and sex-related differences in retinal thickness and foveal pit morphology. Investigative Ophthalmology & Visual Science, 52:625-634. https://doi.org/10.1167/iovs.10-5886
32. Wang, J., Joshi, M., & Lei, Y. (2011). The extent of interlimb transfer following adaptation to a novel visuomotor condition does not depend on awareness of the condition. Journal of Neurophysiology, 106:259-264. https://doi.org/10.1152/jn.00254.2011